town at the apex of the Nile River delta, in Al-Qalyūbīyah (Qalyūbīyah, Al-) muḥāfaẓah (governorate), Lower Egypt. It lies just north of Cairo, near the right bank of the Nile and Barrage Al-Khayrīyah, which controls the division of the Nile's waters into the Rosetta and Damietta branches.

Qalyūb was reputedly constructed with materials taken from the ruins of Heliopolis (modern Miṣr al-Jadīdah), a few miles southeast. Its earliest mention is in AD 641, a year after the Arab invasion of Byzantine Egypt, when the Arab conqueror ʿAmr ibn al-ʿĀṣ built a bridge across the canal there to facilitate subjugation of the towns of Miṣr province. In 1804–05, three years after the Napoleonic forces left Egypt, Qalyūb suffered from depredations by undisciplined soldiery of the Mamlūk sultans. In the mid-19th century Qalyūb lost its status as the capital of the province (now muḥāfaẓah) to Banhā.

The modern town preserves several old mosques, notably the Great Mosque (1182, renovated 1735–36). It is linked to the Cairo-Alexandria superhighway and serves as a railway junction for several lines fanning through the delta. Its industries include cotton and silk weaving. Pop. (1996) 97,157.