French satiric poet whose works recall those of Horace, Juvenal, Ariosto, and Ronsard in free and original imitation, written in vigorous, colloquial French. Writing about typical characters of his time with verve and realism, in alexandrine couplets, he fully displayed his talents in Macette (1609), a work that has been compared to Molière's Tartuffe. An acute critic, Régnier castigated François de Malherbe in an attack on the theory that poetry must conform to precise classical and intellectual standards (Satire IX, À Monsieur Rapin).

Nephew of the poet Philippe Desportes, he became secretary to Cardinal François de Joyeuse and accompanied him to Rome in 1583; his dissolute ways, however, impeded his advancement. Returning to France about 1605, he accepted the protection of Desportes. In 1609 he became canon of Chartres and spent many of his remaining years at the Abbey of Royaumont, near Asnières-sur-Oise.