Venezuelan literary historian and man of letters who played a major role in bringing the works of Latin American writers to world attention.

Jailed during the early years of the dictatorship (1908–35) of Juan Vicente Gómez (Gómez, Juan Vicente), Blanco-Fombona fled to Europe, where he established Editorial América in Madrid (1914), which presented Latin American writers to the European literary world. A prolific author, he wrote poetry, short stories, novels, and essays.

Of Blanco-Fombona's vast output, his literary essays are considered his best work. Two of his critical works, El modernismo y los poetas modernistas (1929; “Modernism and the Modernist Poets”) and Camino de imperfección, diario de mi vida (1906–1913) (1929; “Road of Imperfection, Diary of My Life 1906–1913”), are considered standard works on the Modernist movement (Modernismo) in Spanish. Other important works include Letras y letrados de Hispano-América (1908; “Letters and the Learned in Latin America”) and Grandes escritores de América (1919; “Great Writers of America”). His novel, El hombre de oro (The Man of Gold), was published in 1912.