Italian physiologist and physicist who was the first to explain muscular movement and other body functions according to the laws of statics and dynamics.

He was appointed professor of mathematics at Messina in 1649 and at Pisa in 1656. In 1667 he returned to Messina and in 1674 went to Rome, where he lived under the protection of Christina, former queen of Sweden. His best-known work is De Motu Animalium (1680–81; “On the Movement of Animals”), in which he sought to explain the movements of the animal body on mechanical principles; he thus ranks as the founder of the iatrophysical school.

Borelli also wrote many astronomical works, including a treatise in 1666 that considered the influence of attraction on the satellites of Jupiter. In a letter published in 1665 under the pseudonym Pier Maria Mutoli, he was the first to suggest the idea that comets travel in a parabolic path.