Arabic title of respect, restricted, after the advent of Islam, to members of Muhammad's clan of Hāshim—in particular, to descendants of his uncles al-ʿAbbās and Abū Ṭālib and of the latter's son ʿAlī by Muhammad's daughter Fāṭimah. In the Hejaz (western coast of Arabia), the title of sharif is said to have been further restricted to the descendants of Ḥasan, the elder son of ʿAlī and Fāṭimah. Sharifs originally were heads of prominent families in a town. Later they supplied the local semiautonomous rulers of Mecca and Medina, especially when the cities were under the suzerainty of Baghdad and Cairo, while after the establishment of Ottoman rule, the Ottomans normally recognized the senior representative of the sharifs as prince of Mecca.