private coeducational institution of higher education in Los Angeles, California, U.S. It comprises the College of Letters, Arts, and Sciences, the Graduate School, and 18 professional schools. The university offers undergraduate degrees in about 75 fields and graduate and professional degrees in about 125 disciplines. It is especially well known for its degree programs in film, law, music, public administration, physical therapy, business, engineering, and social work. Total enrollment is approximately 32,000.

USC is one of the largest and best-funded research universities in the country. It operates some 100 research institutes, including the National Center for Integrated Photonic Technology, the Southern California Earthquake Center, the Institute for Robotics and Intelligent Systems, and the Population Research Laboratory. The university contains about 20 libraries, and its holdings include a notable cinema and television collection. In addition to the main University Park campus, the university includes a health sciences campus in northeastern Los Angeles and satellite campuses at Irvine, Sacramento, and Washington, D.C. A marine science centre is located on Santa Catalina Island.

The University of Southern California was incorporated by the Methodist Episcopal church in 1880; it opened the same year. After his arrival in 1917, philosopher Ralph Tyler Flewelling (Flewelling, Ralph Tyler) established USC as a bastion of personalism. In the 1920s the university created one of the country's first schools of international relations and of public administration, as well as a pioneer program in cinematography. The first doctoral degree was awarded in 1923. The university officially became nonsectarian in 1926. Architect Konrad Wachsmann (Wachsmann, Konrad) joined the faculty in 1963 and initiated a doctoral program in building science.

The university has a distinguished history of athletic programs and has produced more Olympic athletes than any other school in the country. Among the athletes who attended USC are sprinter Charlie Paddock (Paddock, Charlie), shot-putter Parry O'Brien (O'Brien, Parry), and gridiron football player O.J. Simpson (Simpson, O.J.). Other alumni include General H. Norman Schwarzkopf (Schwarzkopf, H. Norman), composer Charles Wakefield Cadman (Cadman, Charles Wakefield), architect Frank Gehry (Gehry, Frank O.), actor John Wayne (Wayne, John), director José Quintero (Quintero, José), and filmmaker George Lucas (Lucas, George).