American novelist whose writing style and subject matter reflect the so-called punk sensibility that emerged in the 1970s.

Acker studied classics at Brandeis University and the University of California, San Diego. Her early employment ranged from clerical work to performing in pornographic films. In 1972 she began publishing willfully crude, disjointed prose that drew heavily from her personal experience and constituted a literary analog to contemporary developments in music, fashion, and the visual arts. From the outset, Acker blatantly lifted material from other writers, manipulating it for her own often unsettling purposes. In the early novel The Childlike Life of the Black Tarantula (1973), this process of appropriation is central to the narrator's quest for identity. The book's themes of alienation and objectified sexuality recur in such later novels as Great Expectations (1982), Blood and Guts in High School (1984), Don Quixote (1986), and Empire of the Senseless (1988). In 1991 a collection of some of Acker's early works were published under the title Hannibal Lecter, My Father. This was followed by My Mother: Demonology (1993), which consists of seven love stories. Her 1996 novel, Pussy, King of the Pirates, was adapted for the stage by the seminal punk band the Mekons. The band and Acker released a CD under the same title.

Her works elicited frequent comparison with those of William S. Burroughs (Burroughs, William S.) and Jean Genet (Genet, Jean), and Acker herself cited the influence of the French nouveau roman, or antinovel.