Dientzenhofer was the son of architect Christoph Dientzenhofer (Dientzenhofer, Christoph), with whom he worked professionally. Among Dientzenhofer's individual works are the church of St. Thomas (1725–31; a Gothic structure reworked into Baroque) and the church of St. John on the Rock (1730–39; including the Vyšehrad Steps), both of which are in Prague, as well as the church of St. Mary Magdalene, Karlsbad (now Karlovy Vary; 1733–36). He also built the Villa Amerika (1712–20; afterward the Antonin Dvořák Museum), Prague.