historical town and capital of Loir-et-Cher département, Centre région, north-central France. It lies southwest of Paris and 20 miles (30 km) northwest of Blois. Vendôme stands on the Loir River, which divides and intersects the town. To the south stands a hill on which are ruins of the 11th-century castle of the counts (later dukes) of Vendôme. The town was extensively damaged during World War II but was thereafter largely restored.

The Roman Vindocinum was a provincial fortification of Gaul, replaced later by a feudal castle, around which the town arose. Christianity was introduced by St. Bienheuré in the 5th century, and the important Abbey of the Trinity was founded about 1030. When the reign of the Capetian dynasty began, Vendôme was the chief town of a countship belonging to Bouchard, called “the Venerable.” The succession passed by various marriages to the houses of Nevers, Preuilly, Montoire, and Bourbon. The countship of Vendôme was raised to the rank of a duchy and peerage of France for Charles de Bourbon (1515); his son Anthony (Anthony Of Bourbon), king of Navarre, was the father of Henry IV, who gave the duchy of Vendôme in 1598 to his natural son César (1594–1665), in whose line the dukedom continued for more than a century. The last of the family in the male line (1654–1712) was Louis XIV's famous general, Louis-Joseph, Duke de Vendôme.

Household appliances, electronics, and automobile, aeronautic, and computer parts are manufactured in modern-day Vendôme. Printing and food processing are important, and the tourism sector is growing. Pop. (1999) 17,707; (2005 est.) 17,200.