city, seat (1883) of Mesa county, western Colorado, U.S. It lies in the Grand Valley (elevation 4,586 feet 【1,398 metres】), at the confluence of the Colorado and Gunnison rivers. Settled by ranchers in 1881 after the expulsion of the Ute Indians, it was first called Ute, then West Denver, and was finally named for the junction of the rivers. It developed as the centre of a mining and irrigated-farm region (including, after the late 1980s, many productive vineyards) and as the transportation hub of the Colorado Plateau.

In the 1950s Grand Junction became a business headquarters for uranium production, along with local oil, gas, vanadium, gilsonite, and oil-shale resources. The city grew rapidly in the 1990s, with many new residents having retired and relocated from other parts of the United States. Nearby is the lake-studded Grand Mesa, the Colorado National Monument, and the Grand Mesa and Uncompahgre national forests. Grand Junction is the site of Mesa State College (1925) and of area offices of the U.S. Department of Energy and Bureau of Land Management. Inc. town, 1882; city, 1891. Pop. (1990) 29,034; (2000) 41,986.