first Zand (Zand Dynasty) ruler of Iran. He restored peace to the kingdom after the strife following the collapse of the Ṣafavid dynasty.

Of humble tribal origin, Karīm Khān became one of the generals of his predecessor, Nāder Shāh (Nādir Shāh). In the chaotic aftermath of Nāder Shāh's assassination in 1747, Karīm Khān became a major contender for power but was challenged by several adversaries. In order to add legitimacy to his claim, Karīm Khān in 1757 placed on the throne the infant Shāh Ismāʿīl III, the grandson of the last official Ṣafavid king. Ismāʿīl was a figurehead king, real power being vested in Karīm Khān, who never claimed the title of shāhānshāh (“king of kings”) but used that of vakīl (“regent”).

By 1760 Karīm Khān had defeated all his rivals and controlled all of Iran except Khorāsān, in the northeast, which was ruled by Shāh Rokh, the blind grandson of Nāder Shāh. During Karīm Khān's rule Iran recovered from the devastation of 40 years of war. He made Shīrāz his capital, constructing many fine buildings. Moreover, he reorganized the fiscal system of the kingdom, removing some of the heavy burdens of taxation from the agricultural classes. An active patron of the arts, he attracted many scholars and poets to his capital.

Karīm Khān also opened Iran to foreign influence by allowing the English East India Company to establish a trading post in Bushire, the Persian Gulf port (1763). In advancing his policy of developing trade, in 1775–76 he attacked and captured Basra, the Ottoman port at the mouth of the Persian Gulf, which had diverted much of the trade with India away from Iranian ports.

The civil war that followed Karīm Khān's death ended only with the final establishment of the Qājār dynasty in 1796.