American medical researcher and health educator, known for her determined work in combating AIDS and HIV through research and education.

Krim was educated at the University of Geneva (B.S., 1948; Ph.D., 1953). She worked on biomedical research projects at the Weizmann Institute of Science at Rehovot, Israel (1953–59), and at Cornell Medical College in New York City (1959–62) before becoming a researcher at New York's Memorial Sloan-Kettering Cancer Center in 1962; she eventually became head of the interferon laboratory. She later worked in the department of pediatrics at St. Luke's Roosevelt Hospital Center and Columbia University, New York City (1986–90). From 1990 Krim was adjunct professor of public health and management at Columbia University. In 2000 she was awarded the Presidential Medal of Freedom.

After 1980 Krim devoted her time and energy to fighting AIDS, establishing the AIDS Medical Foundation in 1983. Two years later it merged with a similar organization to form the American Foundation for AIDS Research (AmFAR). Most of AmFAR's funds went to research. The organization was also instrumental in the development of community-based clinical research trials and was active in education and lobbying efforts. AmFAR's efforts resulted in health care services for AIDS patients and debates on controversial policy issues, such as condom distribution in schools and the legal entry of HIV-infected people into the United States.