French literary prize for the best novel published in France each year by a man or woman. The monetary award is 5,000 French francs, and the jury consists of women of letters.

The prize was established in 1904 by the reviews Fémina and Vie Heureuse as an alternative to the Prix Goncourt, which was then unlikely to be given to works written by women. The Prix Fémina-Vacaresco for nonfiction was established in 1937, and foreign works are awarded the Prix Fémina Étranger. Laureates include Pierre Fleutiaux in 1990 for Nous sommes eternals, Sylvie Germain in 1989 for Jours de colere, and Louise Bellocq in 1960 for La Porte retombée.