词条 | mastitis |
释义 | mastitis pathology ![]() Chronic mastitis (fibrocystic disease of the breast) is usually a secondary effect of systemic diseases such as tuberculosis, fungal infections, yeast infections, or syphilis. A relatively uncommon type of mastitis, called plasma cell mastitis, occurs most frequently in older women who have had a number of children and have a history of difficulty in nursing. It is sometimes difficult to distinguish from cancer of the breast. In this disease lymphatic fluids stagnate in the breast, and the stagnated fluids are treated by the body as foreign objects. Plasma cells, white blood cells, and fatty acid crystals accumulate, and fatty tissue suffers degeneration. A hard lump forms under part of the nipple; there may be distortion of the nipple because of the lesion. The nipple area is painful, tender, and inflamed and may exude a cloudy discharge. The milk ducts and lymph nodes are commonly thickened and enlarged. As the condition progresses, small areas of the breast become hardened as the original tissue is destroyed and replaced by fibrous or granular tissue. Injury to the breast tissue is sometimes followed by inflammation and necrosis (death) of the fatty tissue resulting in a hard fixed lump with no skin discoloration. The symptoms of mastitis may be present for many years or may arise after a disease of the breast that involves purulent discharges and abscesses. Economically, bacterial mastitis is a serious disease of dairy cattle. It is spread by milking machines, by the hands of milkers, and by flies. An afflicted animal may develop gangrene, characterized by discoloration of the teats or udder. |
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