city, central Chiapas estado (state), southeastern Mexico. It is situated on the central plateau of the Chiapas Highlands, at an elevation of 6,900 feet (2,100 metres). San Cristóbal is a major cultural and political centre for the Maya and other indigenous peoples of the region.

Founded about 1528 as Villa Real, the settlement was renamed on various occasions before acquiring its present name (1848), which honours Bartolomé de Las Casas (Las Casas, Bartolomé de), the first bishop of Chiapas. Many colonial buildings remain in the city, the most notable of which is the Santo Domingo church, built in the 16th and 17th centuries. The city served as the state capital from its founding until 1892, when its administrative functions were transferred to Tuxtla, 35 miles (60 km) to the west.

Tanning, distilling, flour milling, canning, lumbering, and handicrafts are important industries. However, services account for the largest share of income and employment, and San Cristóbal attracts tourists en route to the Mayan ruins at Palenque. The city's hinterland yields wheat, potatoes, corn (maize), and other crops which, together with forest products, support much of the city's commerce.

In January 1994 San Cristóbal was the scene of intense fighting at the onset of the Zapatista revolt, which continued into the 21st century. The city is linked by highway with Tuxtla, Mexico City, and Guatemala City, and it has an airfield. Pop. (2000) city, 112,442; (2005) urban agglom., 142,364.