tough cord made from the intestines of certain animals, particularly sheep, and used for surgical ligatures and sutures, for the strings of violins and related instruments, and for the strings of tennis rackets and archery bows. The ancient Egyptians and Babylonians and the later Greeks and Romans used the intestines of herbivorous animals for much the same purposes. The origin of the term catgut is obscure; it is not known if the intestines of cats were ever put to such uses.

The intestinal tubes (called runners) of sheep are washed, cut in ribbons, and scraped free of mucous membrane and circular muscle tissue. The ribbons are placed in an alkaline bath for several hours and then stretched on frames. While still moist they are removed, sorted by size, and twisted into cords of varying thickness. A smoothing and polishing operation completes the process.

Italian catgut is considered the best for stringing musical instruments. Surgical catgut is sterilized by heat applied in progressive steps and maintained for several hours; it is often treated with an impregnating agent.