American television soap opera that has been broadcast nearly every weekday since its 1965 debut on the National Broadcasting Company (National Broadcasting Co., Inc.) (NBC) network. The influential series has won numerous Daytime Emmy Awards and has become a fixture of American daytime programming.

Days of Our Lives originally concerned the tumultuous lives of the Horton family, residents of Salem, a fictional Midwestern suburb. But throughout the show's long run, the sagas of additional families, such as the Bradys and DiMeras, were introduced. Like other soap operas, Days of Our Lives often deals with love, family, marriage, adultery, divorce, death, and sex. Many of the show's ongoing story lines have involved characters in protracted, tragic love triangles or with secrets that could harm themselves or their loved ones. Over the years, cast members have frequently changed, with many actors leaving the show and then sometimes returning. Only Frances Reid, who plays matriarch Alice Horton, has been with the show since its debut. MacDonald Carey, who appeared in many Hollywood motion pictures in the 1940s and '50s, played Alice's husband, Dr. Tom Horton, and was the soap's main attraction for many years.

Initially praised for its relatively realistic portrayal of American families and for tackling taboo subjects, the show has in recent decades introduced more action-oriented plots as well as elements of the supernatural. It has attracted an international following and has spent time in the number one daytime slot as well as in the ratings cellar. The show's long run has secured Days of Our Lives (and its familiar over-the-credits introduction, “Like sands through the hourglass, so are the days of our lives”) a place in television history.