U.S. actor, songwriter, and popular playwright, one of the most popular actors of his day. He was one of a select number of Americans to win the ribbon of the French Société Histoire Dramatique.

Born of Irish parents and reared on the Lower East Side of New York City, Florence worked at various jobs before becoming a call boy at the Old Bowery Theatre. While working to support his widowed mother and her seven younger children, he rehearsed plays at night, and in 1850 he began to do dialect impersonations. In 1853 he married Malvina Pray, and thereafter the two generally appeared together on the stage—he usually as an Irishman and she as a Yankee.

Florence's first success was in A Row at the Lyceum (1851); following this, he established his reputation as Captain Cuttle in Dombey and Son, Bob Brierly in The Ticket-of-Leave Man, and Sir Lucius O'Trigger in The Rivals. His last appearance was with Joseph Jefferson, with whom he had maintained a successful partnership.