U.S. inventor of a full-sized grain reaper that was in wide use throughout Illinois, Maryland, New York, and Pennsylvania until Cyrus Hall McCormick's (McCormick, Cyrus Hall) reaper captured the market.

Hussey had invented machines for grinding corn and crushing sugarcane before he began work on a grain-cutting machine in 1830. His reaper made its first successful trial run in July 1833, near Carthage, Ohio, and was patented later that year. McCormick's reaper, first demonstrated in 1831, was patented in 1834. Hussey and McCormick competed fiercely for the reaper market, each patenting improvements and exhibiting machines with great success in the United States and England. Other inventors devised further improvements, which were quickly adopted by McCormick, but Hussey obstinately refused to use the ideas of others. Hussey's business declined, and he sold out in 1858. He died in a train accident, while working on a steam plow.